A microarray analysis, also known as chromosomal microarray or SNP microarray, is a genetic test used by healthcare providers to detect chromosomal abnormalities in children.
A microarray analysis, also known as chromosomal microarray or SNP microarray, is a genetic test used by healthcare providers to detect chromosomal abnormalities in unborn baby. This test looks at chromosomes, which are structures in our cells that contain thousands of genes made of DNA. These genes control our bodies’ growth, function, and characteristics.
Chromosome Basics
Humans usually have 46 chromosomes, which are organised in 23 pairs. Each pair contains one chromosome from the mother and one from the father. The first 22 pairs are identical in size and form in both genders. The 23rd pair, the sex chromosomes, determines genetic gender: females have two X chromosomes, while males have one X and one Y chromosome.
Why is the Test Done?
The microarray analysis detects chromosomal abnormalities that can cause medical conditions such as:
What Does the Microarray Test Detect?
This test does not detect every genetic disease or provide detailed information about specific genes. MCC testing ensures accuracy by checking for contamination from maternal cells.
Amniocentesis
Procedure: A thin needle is inserted into the amniotic sac through the mother’s abdomen to collect amniotic fluid.
When: Typically between 16 and 20 weeks of pregnancy.
Safety: Generally safe, with a minimal risk of complications like miscarriage or infection.
Chorionic Villus Sampling (CVS)
Procedure: Using a needle, a sample of placental tissue (chorionic villi) is taken through the cervix or abdomen.
When: Usually between 10 and 13 weeks of pregnancy.
Safety: Generally safe, but slightly higher miscarriage risk compared to amniocentesis.
Blood Sample
Procedure: A small amount of blood is drawn from the mother’s vein.
Safety: Standard and safe with minimal risks.
Laboratory Process
Turnaround Time: 12-15 working days.
Who needs it?
Is it safe?
Amniocentesis and CVS are both safe when performed by qualified healthcare experts.
Blood sampling is a routine and low-risk procedure.
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